Top 7 Best Supplements for Hangover in 2025

Waking Up Refreshed: Your Guide to the Best Hangover Supplements

Hangovers can ruin your productivity. This listicle reveals the best supplements for hangover relief in 2025. Discover seven top-rated options, including Upside Hangover Sticks, DHM Detox, Flyby Recovery, Cheers Restore, Liquid IV, Thorne Liver Cleanse, and Drinkwel. Whether you’re a busy professional or enjoy occasional nights out, find the perfect supplement to conquer your next hangover and reclaim your day.

1. Upside Hangover Sticks

Searching for the best supplements for hangover relief? Upside Hangover Sticks offer a compelling solution for those seeking a natural, convenient, and effective way to combat the morning-after blues. These innovative jelly sticks are designed to help you recover quickly after a night of indulging in alcoholic beverages, allowing you to reclaim your day and feel your best. Developed with a blend of ingredients rooted in traditional Korean medicine, Upside aims to provide a refreshing alternative to traditional hangover remedies. Whether you're a social drinker, a nightlife enthusiast, a busy professional, or a frequent traveler, Upside Hangover Sticks are designed to seamlessly integrate into your lifestyle and help you balance celebration with well-being.

One of the most appealing aspects of Upside Hangover Sticks is their unparalleled convenience. Forget bulky bottles or complicated pill organizers. These pocket-sized sachets are incredibly easy to carry anywhere, making them ideal for those constantly on the go. Simply slip a few sticks into your bag or pocket before a night out, and you're prepared for whatever the evening brings. When you're ready, just open a sachet, consume the delicious jelly, and let the natural ingredients work their magic. This effortless approach to hangover relief eliminates the need for pre-planning or remembering complex dosing schedules.

Upside distinguishes itself from other hangover supplements through its commitment to using natural ingredients inspired by traditional Korean medicine. This approach resonates with health-conscious individuals seeking alternatives to synthetic remedies. Moreover, Upside is formulated to be free from common allergens and dietary restrictions. It's soy-free, gluten-free, non-GMO, vegan, nut-free, and dairy-free, making it a suitable option for a wide range of dietary needs and preferences. This inclusive approach further solidifies Upside's position among the best supplements for hangover relief.

The effectiveness of Upside Hangover Sticks is not just based on its carefully selected ingredients; it’s also backed by positive customer testimonials. Users frequently praise the product's great taste and noticeable effectiveness in alleviating hangover symptoms. Many report feeling significantly better the morning after a night of drinking, allowing them to enjoy their mornings and social experiences to the fullest. These positive reviews, coupled with the brand's commitment to quality, contribute to Upside’s reputation as a reliable and effective hangover solution.

While Upside offers a compelling solution for many, it's important to consider both the pros and cons. On the plus side, the convenient jelly format, natural ingredients, allergen-free formulation, and positive customer reviews make it a strong contender in the hangover supplement market. The simple, "open-and-eat" design eliminates any guesswork and makes it incredibly user-friendly. However, one potential drawback is the lack of publicly available pricing information. Potential customers need to visit the official Upside website to view current offers and subscription options, which can be slightly inconvenient for those seeking quick price comparisons. Additionally, while Upside has proven effective for many, it may not entirely prevent hangovers for individuals who consume very large amounts of alcohol or those with specific intolerances.

For those seeking specific pricing information, a visit to the Upside website (https://enjoyupside.com) is necessary. While the exact cost isn't readily available elsewhere, the website provides detailed information on subscription options and potential discounts. Considering the convenience, natural formulation, and positive customer feedback, Upside Hangover Sticks offer a valuable investment for those seeking a reliable and enjoyable way to mitigate the effects of alcohol consumption.

In conclusion, if you're looking for the best supplements for hangover, Upside Hangover Sticks are definitely worth considering. Their unique combination of convenience, natural ingredients, and proven effectiveness makes them a standout option for anyone looking to enjoy a night out without sacrificing the next morning. While individual results may vary, Upside’s commitment to quality and positive customer reviews solidify its position as a leading contender in the battle against hangovers.

2. DHM Detox (Dihydromyricetin)

If you're looking for a proactive approach to hangover prevention, DHM Detox (Dihydromyricetin) is a supplement worth considering. Unlike remedies you take after a night out, DHM Detox is designed to be taken before you start drinking, aiming to minimize the unpleasant after-effects before they even begin. This positions it as a unique contender among the best supplements for hangover relief. It leverages the power of dihydromyricetin (DHM), a bioactive flavonoid extracted from the Japanese raisin tree ( Hovenia dulcis ), known for its potential liver-protective properties. The supplement focuses on supporting your liver's ability to metabolize alcohol more efficiently and reducing the inflammation that contributes to hangover symptoms. This preemptive strike against hangover misery makes it a particularly appealing option for those seeking to enjoy social occasions without sacrificing the next day.

Each DHM Detox capsule contains 300mg of pure dihydromyricetin. The formula also includes milk thistle and N-acetyl cysteine, two other ingredients known for their liver-supporting benefits. This combination works synergistically to bolster your body's natural defenses against the negative impacts of alcohol. For vegans and those mindful of additives, DHM Detox capsules are vegan-friendly and free from artificial ingredients. The supplement's formulation is grounded in scientific research, with published studies supporting DHM's effectiveness in mitigating alcohol's effects. Furthermore, DHM Detox is third-party tested for both purity and potency, ensuring you're receiving a high-quality and reliable product.

For busy professionals, frequent travelers, and nightlife enthusiasts who value their time and productivity, a preventative approach to hangovers can be a game-changer. Imagine being able to enjoy a social evening and wake up feeling refreshed and ready to tackle the day ahead. DHM Detox offers precisely this possibility. Instead of relying on post-drinking remedies that may or may not alleviate your symptoms, DHM Detox aims to prevent them from taking hold in the first place. Understanding what causes hangovers can further inform your choices regarding alcohol consumption and preventative measures. Learn more about DHM Detox (Dihydromyricetin)

While DHM Detox offers a promising approach to hangover prevention, it's essential to weigh the pros and cons. On the plus side, it is based on legitimate scientific research demonstrating DHM's efficacy. The preventative approach often yields better results than trying to treat a hangover after it sets in. The supplement boasts a clean ingredient profile with minimal fillers. It's also generally well-tolerated, with few reported side effects. However, DHM Detox is relatively expensive, typically costing between $40 and $50 per bottle. The necessity of taking it before drinking means it won't help if you've already started experiencing hangover symptoms. Availability can also be an issue, as it's primarily sold online and may not be readily available in physical stores. Lastly, as with any supplement, individual responses can vary, and DHM Detox may not work equally well for everyone. This is especially true for those with underlying health conditions, who should consult their physician before incorporating any new supplements into their regimen.

If you're a health-conscious individual seeking an evidence-backed method to mitigate hangover symptoms, DHM Detox presents a compelling option among the best supplements for hangover. Its preventative approach, combined with its scientifically-supported formulation and clean ingredient profile, makes it a valuable tool for those looking to enjoy social drinking responsibly and minimize the negative consequences. You can find more information and purchase DHM Detox on their website: https://dhmdetox.com

3. Flyby Recovery

Flyby Recovery is a popular choice among those seeking a comprehensive solution to combat hangovers. This supplement distinguishes itself through a multi-pronged approach, tackling various contributing factors to that dreaded morning-after feeling. Instead of focusing on a single ingredient, Flyby Recovery incorporates a blend of vitamins, minerals, and herbal extracts designed to support your body before, during, and after alcohol consumption. This makes it a strong contender for anyone looking for the best supplements for hangover relief. It aims to replenish depleted nutrients, support liver function, and rehydrate your body, potentially minimizing the intensity and duration of hangover symptoms. This proactive strategy resonates with many who prefer a preventative measure rather than simply addressing symptoms after they arise.

One of the key selling points of Flyby Recovery is its well-rounded formula. It includes a potent dose of B-complex vitamins, crucial for energy production and often depleted by alcohol consumption. Vitamin C, a powerful antioxidant, is also included to help combat oxidative stress induced by alcohol. Electrolytes like sodium and potassium are added to address dehydration, a major contributor to hangover symptoms like headaches and fatigue. Furthermore, the inclusion of liver-supporting herbal extracts like milk thistle and prickly pear, along with ginger for nausea relief, demonstrates a holistic approach to hangover prevention.

For social drinkers, nightlife enthusiasts, and busy professionals who enjoy occasional drinks but want to minimize the impact on their productivity and well-being, Flyby Recovery presents a convenient option. The two-capsule serving size, packaged in easy-to-swallow veggie capsules, simplifies the process. The recommended dosage involves taking two capsules before your first drink and another two after your last drink. While this two-dose approach might be slightly less convenient than a single-dose supplement, it aligns with the supplement’s strategy of preparing your body for alcohol intake and then supporting recovery afterward.

Frequent travelers who experience disruptions to their routines and sleep patterns might also find Flyby Recovery helpful. The supplement can help mitigate the effects of jet lag and occasional indulgent evenings, allowing them to stay on top of their schedules. Health-conscious individuals who are mindful of what they put into their bodies will appreciate the transparent labeling and GMP certification, signifying adherence to good manufacturing practices. The product is made in an FDA-registered facility, further reinforcing its quality and safety standards.

Flyby Recovery is reasonably priced at around $25-30 per bottle, placing it in a competitive price range compared to other hangover supplements on the market. This affordability makes it accessible to a wider audience. However, despite its comprehensive formula and positive customer reviews, some users report minimal effectiveness. Individual responses to supplements can vary, and factors like metabolism, alcohol tolerance, and overall health can influence the outcome. It is essential to remember that Flyby Recovery, like any supplement, is not a magic bullet and works best when combined with responsible drinking habits and adequate hydration.

It is also crucial to note potential drawbacks. The multiple ingredients in Flyby Recovery may cause interactions with certain medications or pre-existing conditions. Individuals with allergies or sensitivities should carefully review the ingredient list before use. The need for two separate doses (before and after drinking) can also be a minor inconvenience, especially if forgotten. While Flyby Recovery offers a promising approach to hangover prevention, it is advisable to consult with a healthcare professional to determine if it’s the right choice for your individual needs. You can find more information and purchase Flyby Recovery on their website: https://flybyrecovery.com.

4. Cheers Restore

Cheers Restore stands out among the best supplements for hangover relief due to its proactive approach. Rather than addressing symptoms after the fact, Cheers Restore focuses on preparing your body for alcohol consumption, aiming to minimize the negative effects before they even start. This makes it a particularly attractive option for those who enjoy social drinking but want to avoid the dreaded next-day slump. It's formulated with a blend of ingredients designed to support liver function, accelerate alcohol metabolism, and replenish essential nutrients depleted by alcohol. This strategy allows you to enjoy your evening without sacrificing productivity or well-being the following day.

At the heart of Cheers Restore's formula is dihydromyricetin (DHM), a flavonoid extracted from the Japanese raisin tree. Studies suggest DHM can help the body metabolize alcohol more efficiently and may even protect against some of the damaging effects of acetaldehyde, a toxic byproduct of alcohol metabolism. Each serving of Cheers Restore packs a potent 200mg dose of DHM. This is complemented by prickly pear extract, known for its anti-inflammatory properties, which can help combat the inflammation often associated with alcohol consumption. Furthermore, the formula includes milk thistle, a traditional liver support remedy, and a blend of B vitamins and vitamin C to replenish vital nutrients often depleted when drinking.

For busy professionals, frequent travelers, and nightlife enthusiasts, the pre-drinking approach of Cheers Restore offers a convenient solution. Instead of scrambling for a remedy after a night out, you can simply take Cheers Restore before you start drinking. This proactive strategy can be particularly beneficial for those with demanding schedules who can’t afford to lose a day to a hangover. Health-conscious individuals will appreciate the supplement’s focus on liver support and its gluten-free, vegan-friendly formulation. The subscription option available on the Cheers Health website (https://cheershealth.com) provides a hassle-free way to maintain a consistent regimen, ensuring you always have Cheers Restore on hand.

The cost of Cheers Restore is relatively reasonable, priced at approximately $30-35 per bottle. This positions it competitively within the market of best supplements for hangover, offering a good balance of price and purported benefits. While the price point may be higher than some single-ingredient remedies, the comprehensive formula and focus on preemptive action make it a worthwhile investment for many. Compared to other hangover supplements that focus on post-drinking recovery, Cheers Restore’s preemptive approach offers a unique advantage. Other products often rely on electrolytes, pain relievers, and other ingredients to alleviate existing hangover symptoms. Cheers Restore, on the other hand, aims to mitigate these symptoms before they even arise.

While Cheers Restore offers numerous potential benefits, it's important to be aware of its limitations. The supplement is designed to be taken before drinking for optimal results. Taking it after you’ve already consumed alcohol is unlikely to provide significant relief. Some users have also reported experiencing mild stomach upset when taking Cheers Restore on an empty stomach. It's therefore recommended to consume it with food or a substantial snack. As with any supplement, effectiveness can vary significantly between individuals. Factors such as metabolism, body weight, and the amount of alcohol consumed can influence how well Cheers Restore works for you. Finally, the product has limited availability in retail stores, so online ordering is typically required. Despite these limitations, Cheers Restore offers a promising solution for those seeking a proactive approach to hangover prevention, earning its place among the best supplements for hangover. It’s important to remember that no supplement can completely eliminate the effects of alcohol, and responsible drinking habits are always crucial.

5. Liquid IV Hydration Multiplier

Dehydration is a primary culprit behind the unpleasant constellation of symptoms we call a hangover. Alcohol is a diuretic, meaning it promotes fluid loss, leading to an electrolyte imbalance that contributes to headaches, fatigue, and nausea. When searching for the best supplements for hangover relief, rapid rehydration is key, and that's where Liquid IV Hydration Multiplier comes in. This electrolyte drink mix utilizes Cellular Transport Technology (CTT) to deliver hydration more efficiently than water alone, making it a popular choice for those seeking quick relief after a night of indulging.

Liquid IV isn't specifically marketed as a hangover cure, but its effectiveness in combating dehydration has made it a go-to for many hangover sufferers. The science behind CTT involves leveraging the body's natural sodium-glucose co-transport system. By including the optimal ratio of sodium, glucose, and potassium, Liquid IV facilitates the absorption of water into the bloodstream more effectively. This translates to faster rehydration and a quicker recovery from the dehydrating effects of alcohol. Learn more about Liquid IV Hydration Multiplier for a deeper dive into the science of rehydration after drinking.

For the social drinker, the nightlife enthusiast, or even the busy professional who occasionally overindulges, Liquid IV offers a convenient and relatively palatable way to address hangover-related dehydration. The single-serving packets are highly portable, easily slipping into a bag or pocket for on-the-go use. Simply mix the powder with water, and you have a refreshing beverage to help combat the morning-after blues. The availability of various flavors like Lemon Lime, Passion Fruit, and more enhances the experience, making rehydration less of a chore. This is especially appealing when dealing with a sensitive stomach after a night out.

While convenient and effective for rehydration, Liquid IV does have some drawbacks to consider. One significant downside is its sugar content. Each packet contains around 11 grams of sugar, which might be a concern for health-conscious individuals or those watching their sugar intake. Compared to regular electrolyte drinks or homemade rehydration solutions, Liquid IV is also more expensive per serving. Additionally, it’s important to remember that Liquid IV primarily addresses dehydration. It doesn’t target other hangover symptoms like headaches or nausea directly. While rehydration is crucial, it may not be a complete solution for everyone. Finally, some users might be sensitive to the artificial flavorings and colorings used in some flavors.

For comparison, consider traditional sports drinks. While they also offer electrolytes, they often contain even higher amounts of sugar and may not rehydrate as effectively as Liquid IV due to the lack of CTT. Homemade electrolyte solutions using water, salt, and sugar are a much cheaper alternative, but they lack the convenience and precise electrolyte balance of Liquid IV.

Implementing Liquid IV into your hangover recovery strategy is straightforward. Keep a few packets on hand, especially if you anticipate a night of drinking. Upon waking with a hangover, mix a packet with water and consume it immediately. While it's most effective when used as a preventative measure against dehydration, it can still provide significant relief when consumed the morning after. The best supplements for hangover often address multiple symptoms, so consider combining Liquid IV with other remedies targeting specific issues like headache or nausea for a more comprehensive approach to recovery. If you’re looking for a convenient and effective way to combat dehydration, a major component of hangovers, Liquid IV is worth considering, despite its higher price point and sugar content. Just remember to factor in your individual needs and preferences when choosing the best approach for your hangover recovery.

6. Thorne Liver Cleanse

While many supplements on the market target acute hangover symptoms, Thorne Liver Cleanse takes a different approach. This professional-grade supplement focuses on promoting long-term liver health and detoxification, which can indirectly help your body manage alcohol more effectively over time. If you’re seeking a solution for overall liver support that can contribute to better hangover recovery in the long run, Thorne Liver Cleanse is a compelling option amongst the best supplements for hangover. It doesn't offer a quick fix, but rather a proactive strategy for supporting your liver's natural detoxification processes. This makes it especially beneficial for health-conscious individuals, busy professionals, and frequent travelers who may experience occasional or regular alcohol consumption and want to mitigate its impact on their health.

Thorne Liver Cleanse distinguishes itself through its high-quality ingredients and commitment to pharmaceutical standards. The formula features a potent blend of 250mg milk thistle extract (silymarin), a well-regarded herb known for its liver-protective properties. It also includes N-acetylcysteine (NAC), a precursor to glutathione, a powerful antioxidant crucial for detoxification. This combination is further enhanced by alpha-lipoic acid and selenium, providing additional antioxidant support. The inclusion of NAC is particularly relevant for those seeking the best supplements for hangover as it helps replenish glutathione levels that can be depleted by alcohol consumption.

Unlike hangover-specific remedies that you take as needed, Thorne Liver Cleanse is designed for ongoing use to support overall liver health. This proactive approach makes it ideal for social drinkers, nightlife enthusiasts, and busy professionals who want to maintain their liver health despite occasional indulgences. It's not about masking hangover symptoms; it's about giving your liver the tools it needs to function optimally. Learn more about Thorne Liver Cleanse and other liver detox supplements.

Features and Benefits:

• Comprehensive Liver Support: Addresses both detoxification and overall liver health.
• Key Ingredients: Milk thistle extract (silymarin), N-acetylcysteine (NAC), alpha-lipoic acid, and selenium.
• Antioxidant Powerhouse: Helps combat oxidative stress, a key factor in liver damage.
• Quality Assurance: Third-party tested for purity and potency, manufactured to pharmaceutical standards.
• Trusted Brand: Thorne is a reputable supplement company trusted by healthcare professionals.

Pros:

• Premium ingredients and rigorous quality control.
• Addresses the root cause of hangovers by supporting liver health.
• Minimal side effects reported by most users.
• Proactive strategy for long-term liver wellness.

Cons:

• Higher price point ($40-50) compared to some hangover-specific products.
• Not designed for immediate hangover relief.
• Requires consistent, ongoing use for optimal benefits.
• May not be suitable for individuals seeking a quick fix for hangover symptoms.

Implementation and Use:

Thorne Liver Cleanse is taken daily as a dietary supplement. While it can be incorporated as part of a broader strategy for managing hangovers, it’s important to understand that it isn't a quick cure. Consistent use is key to experiencing its full benefits. For individuals looking for immediate hangover relief, combining Thorne Liver Cleanse with other targeted supplements might be a suitable approach. For example, pairing it with a product containing electrolytes and B vitamins could address both long-term liver support and acute dehydration and nutrient depletion associated with hangovers. Always consult with a healthcare professional before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking other medications. This is especially important considering the range of other "best supplements for hangover" options available and the potential for interactions.

Thorne Liver Cleanse is available for purchase on the Thorne website (https://thorne.com). Its focus on preventative liver care sets it apart from other supplements in the "best supplements for hangover" category. By investing in your liver health, you're equipping your body to better manage the effects of alcohol consumption over time. This makes Thorne Liver Cleanse a valuable addition to a holistic approach to wellness, particularly for those who enjoy social drinking but prioritize their long-term health.

7. Drinkwel Multivitamin

If you're looking for a way to support your overall health while enjoying the occasional alcoholic beverage, Drinkwel Multivitamin could be a valuable addition to your routine. Unlike some other supplements on this list that aim to provide immediate hangover relief, Drinkwel takes a proactive approach by replenishing essential nutrients often depleted by alcohol consumption. This makes it a particularly relevant choice for those who drink regularly, rather than those seeking a quick fix after a night out. This daily multivitamin is designed to support your body's natural detoxification processes and minimize the long-term health impacts associated with alcohol.

Drinkwel distinguishes itself from standard multivitamins through its specific formulation targeting the nutritional needs of regular drinkers. It boasts an enhanced B-complex, crucial for energy production and often depleted by alcohol. Furthermore, it includes powerful antioxidants like Vitamin C and E, known for their ability to combat free radicals generated during alcohol metabolism. The inclusion of milk thistle, NAC (N-acetyl cysteine), and alpha-lipoic acid further bolsters liver support and detoxification pathways. These ingredients are known for their potential to protect the liver from damage and promote its efficient functioning. This comprehensive approach makes Drinkwel more than just a multivitamin; it's a targeted supplement designed to mitigate the potential negative effects of regular alcohol consumption.

For busy professionals, social drinkers, frequent travelers, or anyone with a demanding lifestyle that occasionally includes alcohol, Drinkwel offers a convenient way to maintain nutritional balance. Imagine this scenario: you’re traveling for work, attending social events, and perhaps enjoying a few drinks. Keeping track of your nutrient intake can be challenging. Drinkwel simplifies this by providing a comprehensive array of vitamins and minerals in a single capsule. While it won't magically erase the consequences of excessive drinking, its consistent use can contribute to better overall health and potentially lessen the severity of hangover symptoms in the long run.

The supplement is available in vegetarian capsules, free of artificial colors and preservatives, and is formulated by healthcare professionals, adding to its credibility. Drinkwel typically costs between $25-30, making it a reasonably priced option for a complete multivitamin with added benefits for regular drinkers. Many users report positive experiences, highlighting its effectiveness in supporting their overall well-being while enjoying an active social life that includes alcohol.

However, Drinkwel is not a magic bullet for hangovers. It's important to understand that this supplement is designed for daily use, not as an as-needed remedy. If you're looking for a quick fix after a night of heavy drinking, Drinkwel likely won't provide the immediate relief you're seeking. Other supplements on this list, such as those containing electrolytes or DHM, might be more suitable for acute hangover symptoms. Additionally, the relatively large capsule size may pose a challenge for some individuals to swallow comfortably. Finally, for those who rarely drink, a standard multivitamin might be a more cost-effective choice. Drinkwel is specifically formulated for individuals who consume alcohol regularly and therefore might not be necessary for infrequent drinkers.

In comparison to hangover pills designed for immediate relief, Drinkwel offers a different approach. While hangover pills tackle the immediate symptoms, Drinkwel focuses on long-term health maintenance and reducing the negative impacts of regular alcohol consumption. This makes it a valuable tool for those who enjoy alcohol as part of their lifestyle but are also mindful of their health. To incorporate Drinkwel into your routine, simply take one capsule daily with food. Consistent use is key to experiencing its potential benefits.

For more information and to purchase Drinkwel Multivitamin, you can visit their website: https://drinkwel.com Ultimately, Drinkwel offers a proactive strategy for mitigating the potential downsides of regular alcohol consumption, making it a worthy contender among the best supplements for managing the impact of alcohol on your overall health.

Top 7 Hangover Supplements Comparison

Choosing Your Hangover Helper: Final Thoughts

Finding the best supplements for a hangover involves understanding your individual needs and preferences. We've explored seven powerful tools, from the comprehensive approach of Upside Hangover Sticks and Flyby Recovery, to targeted solutions like DHM Detox for acetaldehyde breakdown, Liquid IV for hydration, and Thorne Liver Cleanse for liver support. Remember, the most effective approach depends on your drinking habits and overall health goals. Whether you're a busy professional, a frequent traveler, a health-conscious individual, or simply enjoy the occasional night out, incorporating the right supplement can significantly reduce those dreaded hangover symptoms. Factors to consider include the supplement's ingredients, your individual tolerance, and any existing health conditions. Always consult with a healthcare professional if you have concerns or are taking other medications.

Consistency and informed choices are key when implementing these tools. While these best supplements for hangover can be incredibly effective, they are not a substitute for responsible drinking. Prioritizing hydration, listening to your body's limits, and making smart choices about alcohol consumption are crucial for long-term well-being. These top 7 supplements provide a powerful toolkit to reclaim your mornings and enjoy a healthier, more vibrant you.

Ready to wake up feeling refreshed? Upside Hangover Sticks offer a comprehensive blend of ingredients to tackle hangover symptoms head-on, making them a top contender in the fight against morning-after misery. Learn more and take control of your recovery at Upside Hangover Sticks.